Ademetionine 1,4-butanedisulfonate(SAME)

newstime：2017-09-05 times：

Admetionine 1,4-butanedisulfonate is a common cosubstrate involved in methyl group transfers.

SAME was first discovered in italy by g. l. cantoni in 1952, can preventing liver cancer,promoting

cartilaginous tissue forming and concrescence.

Appearance	Almost white powder ,hygroscopic,soluble in water
Identification (IR spectrum)	1)Chemical reaction should be positive.
Identification (IR spectrum)	2)IR:Should conform with that of the reference substance.
Identification (IR spectrum)	3)HPLC:The retention time of a major peak meets the requirement.
Clarity and color of solution	No more intensely colored than reference solution Y1
pH ( 4 mg/ml solution )	1.8~2.5
Water	≤3.0%
Residue on ignition	≤0.3%
Content	1,4-Butanedisulphonate : 46.0~49.0% (on anhydrous basis )
Content	Ademethionine : 50.0~54.0% (on anhydrous basis,HPLC)
Content	(S,S – isomer ): 60.0 %~75.0% (HPLC)
Related substances (HPLC)	Adenine ≤0.5 %
Related substances (HPLC)	Methylthioadenosine ≤1.0%
Related substances (HPLC)	S- Adenosyl-L-Homocystsine ≤0.5%
Related substances (HPLC)	Other individual impurity:≤0.2%
Related substances (HPLC)	Total other impurities:≤1.0%
Related substances (HPLC)	Total impurities :≤2.5%
Heavy metals	≤10 ppm
Total content	≥96.0 %

Package:1kg/bag,10kg/carton,or as per customer's requirements.

Storage:Store in 2-8℃. Keep away from strong light and heat.

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