Ademetionine disulfate tosylate(SAME)

newstime：2017-09-05 times：

Ademetionine disulfate tosylate is a common cosubstrate involved in methyl group transfers.

SAME was first discovered in italy by g. l. cantoni in 1952, can preventing liver cancer,promoting

cartilaginous tissue forming and concrescence.

Appearance	Almost white powder ,hygroscopic,soluble in water
Identification	1)Chemical reacton 2)IR:consistent with the spectrum obtained with reference substance. 3)HPLC:the retention time of a major peak meets the requirements.
Acid Value	1.0~2.0
Clarity and color of solution	Not more intensely colored than reference solution Y2.
Heavy metals	N.M.T10PPM
Water	N.M.T 2.5%
S-adenosyl-L-Homocystein	N.M.T 0.5%
Methithioadenosine	N.M.T 2.0%
Adenine	N.M.T 0.5%
Related substance	The sum area of unknown impurities must be not more than 1.5times of reference solution main peak’s(1.5%)
(S,S)Isomer	N.L.T 60.0%
Endotoxin	NMT0.3EU/mg
Microbiological	NMT 1000CFU/g
p-toluenesulfonatic acid	21.0%~24.0%(basis on dried)
Sulfates	23.5%~26.5%(basis on dried)
Ademetionine	N.L.T 49.5%(basis on dried)
Total content	N.L.T 96.0%

Package:1kg/bag,10kg/carton,or as per customer's requirements.

Storage:Store in 2-8℃. Keep away from strong light and heat.

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