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Polyinosinic acid (Poly I )

newstime：2017-11-25 times：

PC00.jpg

 

Polyinosinic acid is obtained by Polymerization of IDP under the catalyzation of PNPase,it usually forms a double strand with Polycytidylic acid (Poly C)to Poly I:C, which is a synthetic polyinosinic-polycytidylic acid double-stranded RNA. Poly IC may stimulate the release of cytotoxic cytokines and, by inducing interferon-gamma production, may increase the number and tumoricidal activities of various immunohematopoietic cells.

English name
Polyinosinic acid  (Poly I)
English aliases
Poly I  sodium salt
CAS No.
30918-54-8
Molecular formula
(C10H10O7N4PNa)n
Molecular weight of  residue
352.2
Sedimentation coefficient
>4s
Structural formula
30918-54-8.png 
Physical properties
This product is a white to off-white powder, freely soluble in water, insoluble in ethanol and ether.
pH 7.2, A250/A260 =1.59～1.65; A280/A260 =0.27～0.31; λmax=248nm±1nm.
 
Assay
≥90%
Usage
Its double strand Poly IC, is a synthetic polyinosinic-polycytidylic acid double-stranded RNA. Poly IC may stimulate the release of cytotoxic cytokines and, by inducing interferon-gamma production, may increase the number and tumoricidal activities of various immunohematopoietic cells.
Packing size
500g/bottle,or as per customer’ request.
Storage
Store in the original container,protected from light,in a dry,cool(8~15℃)place. Once it opened, please use it up in a short time.

 

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